| 2010 Top 40 (Original) | ||
| 1 | TIK TOK | KESHA |
| 2 | BAD ROMANCE | LADY GAGA |
| 3 | IN MY HEAD | JASON DERULO |
| 4 | REPLAY | I-YAZ |
| 5 | BREAK YOUR HEART | TAIO CRUZ |
| 6 | SEXY CHICK | DAVID GUETTA |
| 7 | TELEPHONE | LADY GAGA |
| 8 | AIRPLANES | B.O.O/HAYLEY WILLIAMS |
| 9 | CALIFORNIA GIRLS | KATY PERRY |
| 10 | HEY SOUL SISTER | TRAIN |
| 11 | YOU LOVE IS MY DRUG | KESHA |
| 12 | NOTHING ON YOU | B.O.B. |
| 13 | OMG | USHER |
| 14 | DYNAMITE | TAIO CRUZ |
| 15 | BREAKEVEN | THE SCRIPT |
| 16 | WHATCHA SAY | JASON DERULO |
| 17 | COOOLER THAN ME | MIKE POSNER |
| 18 | RUDE BOY | RIHANNA |
| 19 | BILLONAIRE | TRAVIE MCCOY |
| 20 | I LIKE IT | ENRIQUE IGLESIAS |
| 21 | LOVE THE WAY YOU LIE | EMINEM |
| 22 | NEED YOU NOW | LADY ANTEBELLUM |
| 23 | ACCORDING TO YOU | ORIANTHI |
| 24 | IMMA BE | BLACK EYES PEAS |
| 25 | CARRY OUT | TIMBALAND |
| 26 | BULLETPROOF | LA ROUX |
| 27 | ALEJANDRO | LADY GAGA |
| 28 | EMPIRE STATE OF MINE | JAY Z/ALICA KEYS |
| 29 | TEENAGE DREAM | KATY PERRY |
| 30 | DJ GOT US FALLIN IN LOVE | USHER |
| 31 | RIDING SOLO | JASON DERULO |
| 32 | DO YOU REMEMBER | JAY SEAN/SEAN PAULE/LIL JON |
| 33 | BEDROCK | YOUNG MONEY/LLOYD |
| 34 | JUST THE WAY YOUR ARE | BRUNO MARS |
| 35 | WHATAYA WANT FROM ME | ADAM LAMBERT |
| 36 | LIVE LIKE WE'RE DYING | KRIS ALLEN |
| 37 | ALL THE RIGHT MOVES | ONEREPUBLIC |
| 38 | IMPOSSIBLE | SHONTELLE |
| 39 | FIND YOUR WAY | DRAKE |
| 40 | TAKE IT OFF | KESHA |